Genomic analysis and health optimization — variant enrichment with clinical and evolutionary context, plus deep-learning pathogenicity prediction.
Pluribus is a genomic analysis and health-optimization system. The job is to take raw genetic variants and decide which ones actually matter: which are benign, which are suspicious, which deserve clinical follow-up.
The pipeline enriches each variant with clinical-annotation databases (ClinVar and friends), evolutionary conservation scores, population allele frequencies, and protein-level structural impact, then feeds the assembled feature set into deep-learning models for pathogenicity prediction.
Pluribus is the scoring engine of the broader genomics stack. `GeneDrop` is the consumer surface that lets a person upload raw sequencing data and run the checks; the `genes` folder is the HLA-typing wing.